To raise, hoist, or lift a thing using a jack, or similar means.
He jacked the car up to change the tire.
To raise, increase, or accelerate; often said of prices, fees, or rates.
I can't believe they're going to jack up the price of gasoline again — and after they already raised it twenty cents a gallon!
To ruin; wreck; mess up; screw up; sometimes as a bowdlerized substitution for fuck up.
I'm not letting him use my computer again; he always jacks it up.
To give up; to abandon (something, e.g. a job, contract)
To organise something.
To shoot, especially in the context of a poor shot opportunity.
Hoisted, lifted off the ground, or propped up using a jack.
Do you want to rotate the tires while we have the car jacked up?
Describes a 4x4 automobile that has a "lift kit", raising the body and/or frame higher than stock.
He took us for a ride in his awesome new jacked up truck.
Significantly increased or expanded.
It's hard to make ends meet with the jacked up price of gas.
Under the influence of stimulants; high.
They were all jacked up on coke.
Stimulated, excited.
Wrecked; damaged; ruined; injured.
My elbow is all jacked up from playing tennis.
Reprehensible; objectionable.
Dude, your girlfriend left you for your brother? That's jacked up.
Bankrupt; insolvent; ruined; done for.
Absent, having quit, given up, or having abandoned one's post.